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Methods:
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Data annotation and relations modeling for integrated Omics in clinical research.
A. Lukas and B. Mayer
The IIOAB Journal
, 1, 15-23 (
2010
)
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Linking transcriptomics and proteomics data on the level of protein interaction networks.
P. Perco, I. Muehlberger, G. Mayer, R. Oberbauer, A. Lukas, B. Mayer
Electrophoresis
, 31, 1780-1789 (
2010
)
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A dependency graph approach for the analysis of differential gene expression profiles.
A. Bernthaler, I. Muehlberger, R. Fechete, P. Perco, A. Lukas, B. Mayer
Molecular Biosystems
, 5, 1720-1731 (
2009
)
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Analysis and prediction of protective continuous B-cell epitopes on pathogen proteins.
J. Soellner, R. Grohmann, R. Rapberger, P. Perco, A. Lukas, B. Mayer
Immunome Research
, 4:1 (
2008
)
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Characterization of protein-interaction networks in tumors.
A. Platzer, P. Perco, A. Lukas, B. Mayer
BMC Bioinformatics
, 8:224 (
2007
)
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Identification of discontinuous antigenic determinants on proteins based on shape complementarities.
R. Rapberger, A. Lukas, B. Mayer
Journal of Molecular Recognition
, 20, 113-121 (
2007
).
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Transforming omics data into context: Bioinformatics on genomics and proteomics raw data.
P. Perco, R. Rapberger, Ch. Siehs, A. Lukas, R. Oberbauer, G. Mayer, B. Mayer
Electrophoresis
, 27, 2659-2675 (
2006
).
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Machine Learning Approaches for Prediction of Linear B-cell Epitopes on Proteins.
J. Soellner, B. Mayer
Journal of Molecular Recognition
, 19, 200-208 (
2006
).
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Detection of coregulation in differential gene expression profiles.
P. Perco, A. Kainz, G. Mayer, A. Lukas, R. Oberbauer, B. Mayer
Biosystems
, 82, 235-247 (
2005
).
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Reliability of T7-Based mRNA Linear Amplification Validated by Gene Expression Analysis of Human Kidney Cells Using cDNA Microarrays.
M. Rudnicki, S. Eder, G. Schratzberger, B. Mayer, T. Meyer, M. Tonko, G. Mayer
Nephron Experimental Nephrology
, 97, 86-95 (
2004
).
Applications:
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Impaired metabolism in donor kidney grafts after steroid pretreatment.
J. Wilflingseder, A. Kainz, I. Mühlberger, P. Perco, R. Langer, I. Kristo, B. Mayer, R. Oberbauer
Transplant International
, 23, 796-804 (
2010
)
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The role of c-FLIPL in ovarian cancer: chaperoning tumor cells from immunosurveillance and increasing their invasive potential.
A. El-Gazzar, M. Wittinger, P. Perco, M. Anees, R. Horvat, W. Mikulits, T.W. Grunt, B. Mayer, M. Krainer
Journal of Gynecologic Oncology
, 117 451-459 (
2010
)
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Natural immunity enhances the activity of a DR5 agonistic antibody and carboplatin in the treatment of ovarian cancer.
A. El-Gazzar, P. Perco, E. Eckelhart, M. Anees, V. Sexl, B. Mayer, Y. Liu, W. Mikulits, R. Horvat, T. Pangerl, D. Zheng and M. Krainer
Molecular Cancer Therapeutics
9, 1007-1018 (
2010
)
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Systems biology: opening new avenues in clinical research.
F. Molina, M. Dehmer, P. Perco, A. Graber, M. Girolami, G. Spasovski, J.P. Schanstra, A. Vlahou
Nephrology, Dialysis and Transplantation
, 1-4 (
2010
)
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Anti-cancer effects of artesunate in a panel of chemoresistant neuroblastoma cell lines.
M. Michaelis, MC. Kleinschmidt, S. Barth, F. Rothweiler, J. Geiler, R. Breitling, B. Mayer, H. Deubzer, O. Witt, J. Kreuter, HW. Doerr, J. Cinatl, J. Cinatl Jr.
Biochemical Pharmacology
79, 130-136 (
2010
)
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Antithymocyte globulin use for treatment of biopsy confirmed acute rejection is associated with prolonged renal allograft survival.
A. Kainz, R. Korbély, A. Soleiman, B. Mayer, R. Oberbauer
Transplant International
23, 64-70 (
2010
)
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Biocompatibility of peritoneal dialysis solutions determined by genomics of human leucocytes: a cross-over study.
J. Wilflingseder, P. Perco, A. Kainz, C. Schwarz, R. Korbely, B. Mayer, R. Oberbauer
Nephrology, Dialysis and Transplantation PLUS
2, 10-12 (
2009
)
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Chemoresistance acquisition induces a global shift of expression of aniogenesis-associated genes and increased pro-angogenic activity in neuroblastoma cells.
M. Michaelis, D. Klassert, S. Barth, T. Suhan, R. Breitling, B. Mayer, N. Hinsch, HW. Doerr, J. Cinatl, J. Cinatl Jr.
Molecular Cancer
8, 80-94 (
2009
)
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Biomarkers in renal transplantation ischemia reperfusion injury.
I. Mühlberger, P. Perco, R. Fechete, B. Mayer, R. Oberbauer
Transplantation
88, 14-19 (
2009
)
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Neuropilin-1 and neuropilin-2 are differentially expressed in human proteinuric nephropathies and cytokine-stimulated proximal tubular cells.
H. Schramek, R. Sarközi, C. Lauterberg, A. Kronbichler, M. Pirklbauer, R. Albrecht, SJ. Noppert, P. Perco, M. Rudnicki, FM. Strutz, G. Mayer
Laboratory Investigation
89, 1304-1316(
2009
)
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Inter-laboratory comparison of human renal proximal tubule (HK-2) transcriptome alterations due to cyclosporine A exposure and medium exhaustion.
P. Jennings, S. Aydin, J. Bennett, R. McBride, C. Weiland, N. Tuite, L. Gruber, P. Perco, P. O'Gaora, H. Ellinger-Ziegelbauer, HJ. Ahr, C. Van Kooten, MP Daha M Ryan, W. Pfaller, T. McMorrow
Toxicology in-vitro
23, 486-499 (
2009
)
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Microarray and bioinformatics analysis of gene expression in experimental membraneous nephropathy.
P. Hauser, P. Perco, I. Muehlberger, J. Pippin, M. Blonski, B. Mayer, C. Alpers, R. Oberbauer, S. Shankland
Nephron Experimental Nephrology
112, 43-58 (
2009
)
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Molecular predictors for kidney post-transplant anaemia.
J. Wilflingseder, A. Kainz, P. Perco, R. Korbely, B. Mayer, R. Oberbauer
Nephrology, Dialysis and Transplantation
24, 1015-1023 (
2009
)
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Stress Responses and Conditioning Effects in Mesothelial Cells Exposed to Peritoneal Dialysis Fluid.
K. Kratochwill, M. Lechner, Ch. Siehs, H. Lederhuber, P. Rehulka, M. Endemann, D. Kasper, K. Herkner, B. Mayer, A. Rizzi, C. Aufricht
Journal of Proteome Research
8, 1731-1747 (
2009
)
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Hypoxia response and VEGF-A expression in human proximal tubular epithelial cells in stable and progressive renal disease.
M. Rudnicki, P. Perco, J. Enrich, S. Eder, D. Heininger, A. Bernthaler, M. Wiesinger, R. Sarkozi, S. Noppert, H. Schramek, B. Mayer, R. Oberbauer, G. Mayer
Laboratory Investigation
89, 337-346 (
2009
)
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CMV-hyperimmune globulin for preventing cytomegalovirus infection and disease in solid organ transplant recipients: a meta-analysis.
N. Bonaros, B. Mayer, T. Schachner, G. Laufer, A. Kocher
Clinical Transplantation
22, 89-97 (
2008
)
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Histogenomics: Association of gene expression patterns with histological parameters in kidney biopsies.
P. Perco, A. Kainz, J. Wilflingseder, A. Soleiman, B. Mayer, R. Oberbauer
Transplantation
87, 290-295 (
2008
)
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Nanocrystalline versus Detonation Diamond: surface properties and suitability as cell growth support.
T. Lechleitner, F. Klauser, T. Seppi, J. Lechner, P. Jennings, P. Perco, B. Mayer, D. Steinmüller-Nethl, J. Preiner, P. Hinterdorfer, M. Herrmann, E. Bertel, K. Pfaller, W. Pfaller
Biomaterials
29, 4275-4284 (
2008
)
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Biocompatibility of haemodialysis membranes determined by gene expression of human leucocytes: a crossover study.
J. Wilflingseder, P. Perco, A. Kainz, R. Korbely, B. Mayer, R. Oberbauer
European Journal of Clinical Investigation
38, 918-924 (
2008
)
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Bortezomib-induced Survival Signalling and Genes in Human Proximal Tubular Cells.
R. Sarközi, P. Perco, K. Hochegger, J. Enrich, M. Wiesinger, M. Pirklbauer, S. Eder, M. Rudnicki, A. Rosenkranz, B. Mayer, G. Mayer, H. Schramek
Journal of Pharmacology and Experimental Therapy
327, 645-656 (
2008
)
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Marker of cellular senescence in zero hour biopsies predict outcome in renal transplantation.
Ch. Koppelstaetter, G. Schratzberger, P. Perco, J. Hofer, W. Mark, R. Oberbauer, Ch. Schwarz, Ch. Mitterbauer, A. Kainz, H. Karkoszka, A. Wiecek, B. Mayer, G. Mayer
Aging Cell
7, 491-497 (
2008
)
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Biomarkers for cardiovascular disease and bone metabolism disorders in chronic kidney disease. A systems biology perspective.
P. Perco, J. Wilflingseder, A. Bernthaler, M. Wiesinger, M. Rudnicki, B. Wimmer, A. Kainz, A. Lukas, G. Mayer, B. Mayer, R. Oberbauer
Journal of Cellular and Molecular Medicine
12, 1177-1187 (
2008
)
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Mouse mammary tumor virus integration site selection in human and mouse genomes.
A. Faschinger, F. Rouault, J. Sollner, A. Lukas, B. Salmons, W. Guenzburg, S. Indik
Journal of Virology
82, 1360-1367 (
2008
)
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Linking ovarian cancer transcriptome and immunome.
R. Rapberger, P. Perco, C. Sax, Ch. Siehs, D. Pils, A. Lukas, B. Mayer, M. Krainer
BMC Systems Biology
3:2 (
2008
)
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In vitro transcriptional response of polymorphonuclear leukocytes following contact with different antigens.
K. Hochegger, P. Perco, J. Enrich, B. Mayer, G. Mayer, A. Rosenkranz, M. Rudnicki
European Journal of Clinical Investigation
37, 860-869 (
2007
)
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Gene expression and biomarkers in renal transplant ischemia reperfusion injury.
P. Perco, C. Pleban, A. Kainz, A. Lukas, B. Mayer, R. Oberbauer
Transplant International
20, 2-11 (
2007
)
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Gene-expression profiles of donor kidney biopsies obtained before transplantation distinguish medium term allograft function.
A. Kainz, P. Perco, B. Mayer, A. Soleiman, R. Steininger, G. Mayer, Ch. Mitterbauer, Ch. Schwarz, T. Meyer, R. Oberbauer
Transplantation
83, 1048-1054 (
2007
)
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Gene expression profiles of human proximal tubular epithelial cells in proteinuric nephropathies.
M. Rudnicki, S. Eder, P. Perco, J. Enrich, K. Schreiber, Ch. Koppelstätter, G. Schratzberger, B. Mayer, R. Oberbauer, T. W. Meyer, G. Mayer
Kidney International
71, 325-335 (
2007
)
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Molecular signature of mice T-lymphocytes following tolerance induction by allogeneic BMT and CD40-CD40L costimulation blockade.
P. Perco, P. Blaha, A. Kainz, B. Mayer, P. Hauser, T. Wekerle, R. Oberbauer
Transplant International
19, 146-157 (
2006
)
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Protein biomarkers associated with acute renal failure and chronic kidney disease.
P. Perco, C. Pleban, A. Kainz, A. Lukas, G. Mayer, B. Mayer, R. Oberbauer
European Journal of Clinical Investigation
36, 753-763 (
2006
)
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Identification of a novel melanoma biomarker derived from melanoma- associated endogenous retroviruses.
J. Humer, A. Waltenberger, A. Grassauer, M. Kurz, J. Valencak, R. Rapberger, K. Wolff, T. Muster, B. Mayer, H. Pehamberger
Cancer Research
66, 1658-1663 (
2006
)
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Transcriptional response in the unaffected kidney after contralateral hydronephrosis or nephrectomy.
P. Hauser, A. Kainz, P. Perco, H. Bergmeister, C. Mitterbauer, Ch. Schwarz, H. M. Regele, B. Mayer, T. W. Meyer, R. Oberbauer
Kindey International
68, 2497-2507 (
2005
)
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Impaired tubular cell cycle regulation and activated immune response in transplant kidney biopsies from cadaveric compared to live organ donors.
A. Kainz, Ch. Mitterbauer, P. Hauser, Ch. Schwarz, H. M. Regele, G. Berlakovich, G. Mayer, P. Perco, B. Mayer, T. W. Meyer, R. Oberbauer
American Journal of Transplantation
4, 1595-1604 (
2004
)
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Genome wide gene expression patterns of donor kidney biopsies distinguish primary allograft function.
P. Hauser, Ch. Schwarz, Ch. Mitterbauer, H. M. Regele, F. Mühlbacher, G. Mayer, P. Perco, B. Mayer, T. W. Meyer, R. Oberbauer
Journal of Laboratory Investigation
84, 353-361 (
2004
)
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Mitochondrial Regulation of Apoptosis.
B. Mayer, R. Oberbauer
News in Physiological Sciences
18, 89-94 (
2003
)
